We compared graft survival (GS) by several variables to find risk factors in pediatric (PD0 renal transplants (RT), and checked the height (HT) promotion in successful PD RT based on 52 PD RT. In 31 patients (PT), original disease was identified:
nephropathy (10), Alport syndrome (7), FSGS (5), MPGN (3), congenital hypo/dysplastic kidney (2), IgA nephropathy (2), chronic GN (4), Either trans(14)-or extra(38)-peritoneal approach was employed according to the size or weight of PT. One cases
of
perinephric hematoma requiring reoperative intervention occurred. Two PT were dead of sepsis. Currently, 50 PT are alive with functioning graft in 45. Cause of graft failure (7) was chronic rejection (TR, 3), poor compliance (2), patient death
(2).
One
PT with CR had a 2nd graft. GS at 1 and 5 year (GS-1 & GS-5) was 96.0 and 75.5%. There was no significant difference of GS by the source of donor, degree of HLA match, episode of acute rejection. ABO matching was a significant risk affecting GS:
GS-5 in
identical ABO pair was 91.0% comparing with 41.0% in compatible pairs (p=0.0083). Of 17 PT with complete drecord, 6(35.3%) showed improvement in standard deviation score of HT, and 3(17.6%) showed improvement in HT age. Conclusion: GS in PD PT is
excellent with GS-5 over 75%. ABO matching to be a significant risk factor affecting graft survival. RT may be of benefit in growing children both in aiding psychological problems and in promoting height growth. Therefore, vigorous attempts
should
be
made to perform renal trasplantation in the early stages of ESRD. The importance of early diagnosis & proper management of reflux nephropathy shlould not be overslooked in PD PT with recurrent urinary tract infection.
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